PUBLICATIONS 2018-06-22T18:35:42+00:00

Featured Publications

For more, visit JF Cheer at Pubmed or Google Scholar.

Covey, D.P., Dantrassy, H.M., Yohn, S.E., Castro, A., Conn, P.J., Mateo, Y. & Cheer, J.F. (2018). Inhibition of endocannabinoid degradation rectifies motivational and dopaminergic deficits in the Q175 mouse model of Huntington’s disease. Neuropsychopharmacology.

Wenzel, J.M., Oleson, E.B., Love, W.N., Cole, A.B., Gyawali, U., Dantrassy, H.M., Bluett, R.J., Dryanovski, D.I., Stuber, G.D., Deisseroth, K., Mathur, B.N., Patel, S., Lupica, C.R. & Cheer, J.F. (2018). Phasic dopamine signals in the nucleus accumbens that cause active avoidance require endocannabinoid mobilization in the midbrain. Current Biology,28, 1-13.

Bailey, M.R., Goldman, O., Bello, E.P., Chohan, M.O., Jeong, N., Winiger, V., Chun, E., Schipani, E., Kalmbach, A., Cheef, J.F., Balsam, P.D., & Simpson, E.H. (2018). An interaction between serotonin receptor signaling and dopamine enhances goal-directed vigor and persistence in mice. The Journal of Neuroscience, 38(9), 2149 –2162

Mateo, Y.,  Johnson, K.A., Covey, D.P., Atwood, Wang, H., Zhang, S., Gildish, I., Cachope, R., Bellocchio, L., Guzma ́n, M., Morales, M., Cheer, J.F., & Lovinger, D.M. (2017). Endocannabinoid actions on cortical terminals orchestrate local modulation of dopamine release in the nucleus accumbens. Neuron, 96, 1112–1126.

Cheer, J.F. (2017). A new dawn in cannabinoid neurobiology: The road from molecules to therapeutic discoveries. Neuropharmacology, 124, 1-2.

Wenzel, J. M. & Cheer, J. F. (2017). Endocannabinoid regulation of reward and reinforcement through interaction with dopamine and endogenous opioid signaling. Neuropsychopharmacology, 43, 103-115

Lopatina, N., Sadacca, B. F., McDannald, M. A., Styer, C. V., Cheer, J. F., & Schoenbaum, G. (2017). Ensembles in medial and lateral orbitofrontal cortex construct cognitive maps emphasizing different features of the behavioral landscape. Behavioral Neuroscience131(3), 201-212.

Covey, D. P., Mateo, Y., Sulzer, D., Cheer, J. F., & Lovinger, D. M. (2017). Endocannabinoid modulation of dopamine neurotransmission. Neuropharmacology , 124, 52-61.

Patel, S., Hill, M. N., Cheer, J. F., Wotjak, C. T., & Holmes, A. (2017). The endocannabinoid system as a target for novel anxiolytic drugs.  Neuroscience and BioBehavioral Reviews 76(Pt A), 56-66.

Terrillion, C. E., Dao, D. T., Cachope, R., Lobo, M. K., Puche, A. C., Cheer, J. F., & Gould, T. D. (2017). Reduced levels of Cacna1c attenuate mesolimbic dopamine system function. Genes, Brain and Behavior 16(5), 495-505.

Can, A., Frost, D. O., Cache, R. Cheer, J. F., & Gould, T. D. (2016). Chronic lithium treatment rectifies maladaptive dopamine release in the nucleus accumbens.  The Journal of Neurochemistry139(4), 576-585.

Zlebnik, N. E., & Cheer, J. F. (2016). Drug-Induced Alterations of Endocannabinoid-Mediated Plasticity in Brain Reward Regions. The Journal of Neuroscience36(40), 10230-10238.

Covey, D. P., Zlebnik, N. E., & Cheer, J. F. (2016). Endocannabinoid Regulation of Cocaine Reinforcement: an Upper or Downer? Neuropsychopharmacology 41(9), 2189-2191.

Zlebnik, N. E., & Cheer, J. F. (2016). Beyond the CB1 receptor: Is cannabidiol the answer for disorders of motivation?  Annual Review of Neuroscience.

Covey, D. P., Dantrassy, H. M., Zlebnik, N. E., Gildish, I., & Cheer, J. F. (2016).  Compromised dopaminergic encoding of reward accompanying suppressed willingness to overcome high effort costs is a prominent prodromal characteristic of the Q175 mouse model of Huntington’s disease. The Journal of Neuroscience36(18), 4993-5002.

Can, A., Zanos, P., Moaddel, R., Kang, H. J., Dossou, K. S., Wainer, I. W., … & Gould, T. D. (2016). Effects of ketamine and ketamine metabolites on evoked striatal dopamine release, dopamine receptors, and monoamine transporters.  Journal of Pharmacology and Experimental Therapeutics359(1), 159-170.

Lopatina, N., McDannald, M. A., Styer, C. V., Peterson, J. F., Sadacca, B. F., Cheer, J. F., & Schoenbaum, G. (2016). Medial orbitofrontal neurons preferentially signal cues predicting changes in reward during unblocking.  The Journal of Neuroscience36(32), 8416-8424.

Covey, D. P., Bunner, K. D., Schuweiler, D. R., Cheer, J. F., & Garris, P. A. (2016). Amphetamine elevates nucleus accumbens dopamine via an action potential-dependent mechanism that is modulated by endocannabinoidsEuropean Journal of Neuroscience.

Lopatina, N., McDannald, M. A., Styer, C. V., Sadacca, B. F., Cheer, J. F., & Schoenbaum, G. (2015). Lateral orbitofrontal neurons acquire responses to upshifted, downshifted, or blocked cues during unblocking. eLife, 4, e11299.

Bagot, R. C., Parise, E. M., Peña, C. J., Zhang, H. X., Maze, I., Chaudhury, D., … & Deisseroth, K. (2015). Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature Communications, 6.

Hernandez, G., & Cheer, J. F. (2015). To act or not to act: endocannabinoid/dopamine interactions in decision-making. Frontiers in Behavioral Neuroscience, 9.

Covey, D. P., Wenzel, J. M., & Cheer, J. F. (2015). Cannabinoid modulation of drug reward and the implications of marijuana legalization. Brain Research, 1628, 233-243.

Wang, H., Treadway, T., Covey, D. P., Cheer, J. F., & Lupica, C. R. (2015). Cocaine-induced endocannabinoid mobilization in the ventral tegmental area. Cell Reports12(12), 1997-2008.